Effects on the haematopoetic system slight decreases in the number of erythrocytes and platelets were seen in rats and monkeys.
There have been very rare cases of the following side effects reported following treatment with other fluoroquinolones, which might possibly also occur during treatment with moxifloxacin: In the event of overdose, symptomatic treatment should be implemented. Our goal is to provide you with the most relevant and current information.
AVELOX moxifloxacin hydrochloride is a synthetic antibacterial agent for oral and intravenous administration. There is limited information available on the potential for a pharmacodynamic interaction in humans between AVELOX and other drugs that prolong the QTc interval of the electrocardiogram.
The following in vitro data are available, but their clinical significance is unknown.
In a crossover study involving 24 healthy volunteers 12 male; 12 femalethe mean atenolol AUC following a single oral dose of 50 mg atenolol with placebo was similar to that observed when atenolol was given concomitantly with a single mg oral dose of moxifloxacin. What Avelox is and what it is used for 2. The recommended dose mg once daily and duration of therapy for the indication being treated should not be exceeded. Use caution in patients with a history of diabetes, hepatic impairment, renal impairment, or rheumatoid arthrtitis.
Do not pass it on to others. Worsening of myasthenia gravis a disease which causes muscle weakness. The same dose can be taken by elderly patients, patients with a low bodyweight or in patients with kidney problems. Par- and Dysaesthesia Taste disorders incl. Who should not take Avelox?
The mechanism of action for fluoroquinolones, including moxifloxacin, is different from that of macrolides, beta-lactams, aminoglycosides, or tetracyclines; therefore, microorganisms resistant to these classes of drugs may be susceptible to moxifloxacin. Avoid any unnecessary exercise, as this might increase the risk of a tendon rupture see sections Do not take Avelox… and 4. It cannot be determined if any of the above laboratory abnormalities were caused by the drug or the underlying condition being treated.
View explanations for tiers and restrictions. It is a slightly yellow to yellow crystalline substance with a molecular weight of Possible side effects contact your doctor immediately before you continue treatment.
When Avelox film-coated tablets are used to complete a course of therapy started with Avelox solution for infusion, the recommended durations of use are:. No significant effect of moxifloxacin mg every twelve hours for 3 days on the pharmacokinetics of theophylline mg every twelve hours for 3 days was detected in a study involving 12 healthy volunteers.