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Moderate Concomitant use of clindamycin and darunavir may decrease clindamycin clearance and increase the risk of adverse reactions. Parenteral product contains benzyl alcohol, which has been associated with gasping syndrome and death in newborns. Prophylaxis should not be discontinued in children younger than 1 year of age. Major The lincosamides and phenicol derivatives are bactericidal or bacteriostatic via the same or similar mechanism of action and may have an antagonistic effect.

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Liver function tests LFTs should be monitored regularly during therapy in patients with severe liver disease. Share Email Print Feedback Close. Clinical uses include acne vulgaris, bone and joint infections, and skin and skin structure infections.

Reported clinical experience indicates that antibiotic-associated colitis and diarrhea due to Clostridium difficile seen in association with most systemic antibiotics, such as clindamycin, occur more frequently in the geriatric adult 60 years or older and may be more severe.

Moderate Concomitant use of clindamycin and lopinavir; ritonavir may decrease clindamycin clearance and increase the risk of adverse reactions. Ingredients contained in the suppository base may weaken latex or rubber products i.


Children and Adolescents 12 to 17 years. Send the page " " to a friend, relative, colleague or yourself. Anticonvulsants may be administered to patients with a seizure history during the acute treatment phase; however, they should not be used prophylactically.

Duration of therapy must be individualized; the minimum duration recommended for pediatric patients with MRSA infections is 3 to 4 weeks for septic arthritis and 4 to 6 weeks for osteomyelitis.

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A supplemental dosage is not recommended for CAPD. Positive evidence of human fetal risk. Acetaminophen; Butalbital; Caffeine; Codeine: Clindamycin is used as a single agent for S. Contraindications Hypersensitivity to clindamycin, lincomycin, or formulation components. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

It is unknown whether rifaximin can have a significant effect on the pharmacokinetics of concomitant CYP3A4 substrates in patients with reduced liver function who have elevated rifaximin concentrations.

Prophylaxis to complete an antimicrobial course of up to 60 days may be required. Moderate Concomitant use of clindamycin and griseofulvin may increase clindamycin clearance and result in loss of efficacy of clindamycin.

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The water should be added in 2 portions; shake well after each aliquot. Cobicistat; Elvitegravir; Emtricitabine; Tenofovir Alafenamide: