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Genetic factors comparable to stroke, diabetes in development of CAD.

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Epstein said genotype results typically were not ready for 11 to 60 days after the start of warfarin therapy. For physicians administering warfarin Coumadin, Bristol-Myers Squibb treatment to patients in the outpatient setting, genotyping may help reduced hospitalizations that stem from bleeding or thromboembolism events, according to a study published June 22 in the Journal of the American College of Cardiology.

Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! Back to Top Article Outline.

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Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. These enzymes contribute significantly to how sensitive a patient is to warfarin, and, as a result, the dose that should be used. Neurology in the News Podcast. A must-read every morning. This analysis had two external control groups of 2, patients from each of the two time periods.

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Physicians received the results and recommendations for warfarin dose and frequency of monitoring, with the option of following them. Patients who underwent genetic testing for the warfarin metabolism gene CYP2C9 and the vitamin K blood clotting activator gene VKORC1 had 31 percent fewer total hospitalizations than historical controls, a significant difference, Robert S.

Twenty-two percent of patients who start taking warfarin, a commonly prescribed blood thinner, end up in the hospital within six months, according to health plan data compiled by Medco Health Solutions. Warfarin Genotyping Reduces Hospitalization Rates. Global Resource for Healthcare Professionals.

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The findings were simultaneously published online March 30 in the Journal of the American College of Cardiology. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: MedPulse News App Stay on top of breaking news in your specialty and across medicine.

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Per protocol is where you only follow patients according to the protocol. Joint Accredited with multiple accreditations, including:. Hospitalization rates for these patients were compared with rates of a historical control group of similar patients who began warfarin treatment at the same 23 insurance plans from June to June Patient deoxyribonucleic acid for the two genes were collected, and results were delivered to physicians for interpretation. Comprar e-Livro - RUB The Mayo Clinic then conducted genotype testing on the patients.

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